Takeda-led COVID-19 plasma product to begin trial this month

TOKYO: An experimental COVID-19 therapy using blood plasma, developed by Japan’s Takeda Pharmaceutical and its partners, is scheduled to begin a late-stage clinical trial after initial delays.

The study, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, is seeking to recruit 500 participants from the United States, Britain, Argentina and Denmark, according to a posting on a website run by the US government’s National Institutes of Health (NIH).

The NIAID is an institute of the NIH.

The study, due to begin this month, seeks to compare outcomes from the plasma product to those from the drug remdesivir and a placebo.

READ: US authorises plasma treatment against COVID-19

READ: WHO cautious on using recovered COVID-19 patients’ plasma as US issues emergency authorisation

The Takeda-led group, known as the CoVIg-19 Plasma Alliance, had originally sought to begin trials in July. A Takeda representative said further questions about the study should be directed to the NIAID.

The institute did not immediately respond to a request for comment.

The alliance, which includes Biotest AG, CSL Behring and Octapharma Plasma, is working on a hyperimmune globulin therapy derived from convalescent plasma. It offers a standardised dose of antibodies and does not need to be limited to patients with matching blood types.

READ: 11 recovered COVID-19 patients in Singapore to donate blood for plasma therapy treatment

Clinical supplies of the treatment were produced at Takeda’s facility in the US state of Georgia and at CSL Behring’s facility in Bern, Switzerland.

BOOKMARK THIS: Our comprehensive coverage of the coronavirus outbreak and its developments

Download our app or subscribe to our Telegram channel for the latest updates on the coronavirus outbreak: https://cna.asia/telegram